Combined Imaging of Cl and Na at 7 Tesla: First Results in Brain Tumors

Fig. 2: a) Na MRI of a healthy human brain (Hamming filter). b) Before the calculation of the Cl/Na ratio maps, the Na MRI data was reconstructed with a Gaussian filter (b) to achieve the similar actual spatial resolution than in Cl MRI (c). d) Calculated Cl/Na ratio maps of the healthy human brain. Fig. 3: Glioblastoma patient. a) Contrastenhanced T1-weighted MPRAGE image (B0=3T). b) Cl /Na ratio maps; c) Cl MRI; d) Na MRI. In the area affected by the glioblastoma, the measured C/Na ratio is reduced compared to healthy brain tissue and cerebrospinal fluid. 3631 Combined Imaging of Cl and Na at 7 Tesla: First Results in Brain Tumors Armin M. Nagel, Reiner Umathum, Marc-André Weber, Jan-Oliver Neumann, and Armin Biller Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Germany, Radiology, German Cancer Research Center (DKFZ), Germany, Dpt. of Neurosurgery, University Hospital of Heidelberg, Heidelberg, Germany, Dpt. of Neuroradiology, German Cancer Research Center (DKFZ), Heidelberg, Germany